Sea como fuere, el tratamiento prolongado con nitratos se suele acompañar de En aquellos pacientes que presentan angina de Prinzmetal sobre un fondo de . We present 2 cases of severe vasospastic angina resistant to intensive medical vagal tone associated with thyrotoxicosis triggers prinzmetal variant angina and Un tratamiento a tener en cuenta en la tirotoxicosis inducida por amiodarona. S: Coronary arterial spasm and Prinzmetal’s variant form of angina induced by hyperventilation and Tris-buffer infusion. Circulation 56, A lead ECG was obtained. From the Cattedra di Fisiopatologia Cardiorespiratoria dell.

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CiteScore measures average citations received per document published. A repeated coronary angiography revealed a diffuse, severe spontaneous spasm of anterior descending artery ADA Figure 1which reproduced the admission clinical onset.

The present manuscript strengthens the hypothesis concerning causality in the association between hyperthyroidism and vasospastic angina, which, if sufficiently prolonged, can provoke myocardial infarction. To improve our services fiziopatologia products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. The free thyroxine level was 6.

Thyrotoxicosis-Induced Vasospastic Angina

The main characteristic of the initial clinical course was the difficult management, with frequent anginal episodes, despite the use of high-dose calcium antagonists and nitrates. Previous article Next article. He anhina primary angioplasty with conventional stent implantation in mid ADA. This item has received.

A year-old man was brought to our hospital with acute myocardial infarction and precordial ST elevation. Continuing navigation will be considered as acceptance of this use.

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. The episodes of angina at rest were uncontrollable until diagnosis and proper treatment of the concomitant hyperthyroidism, the onset of which was nearly asymptomatic. From Monday to Friday from 9 a. The cardiovascular effects of hyperthyroidism are well known, and prinzmehal associated with a hyperadrenergic state and an agonist effect of calcium in the myocardium.


The authors wish to thank the reviewers for their comments and the suggested modifications, which contributed considerably to improving the manuscript. Si continua navegando, consideramos que acepta su uso.

The patient was a year-old man with dilated cardiomyopathy and angiographically normal coronary arteries in 2 prior catheterizations. Print Send to a friend Export reference Mendeley Statistics. After having experienced several documented episodes of atrial fibrillation and nonsustained ventricular tachycardia, the patient began to receive treatment with amiodarone, in addition to the carvedilol that he was already taking. With a diagnosis of Graves’ disease, the hyperthyroidism was controlled with carbimazole, and the patient has remained asymptomatic after 8 months of follow-up with no fisiopatopogia for calcium antagonists, which were discontinued 45 days after fisiopatologiw was discharged.

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. December Next article. Once the diagnosis of hyperthyroidism is established, medical treatment usually suffices, although, in severe cases, most of which are induced by amiodarone, thyroidectomy may be necessary. This time, coronary angiography revealed diffuse spasm in mid-distal ADA Figure 2which was controlled with intracoronary nitroglycerin.

Se continuar a navegar, consideramos que aceita o seu uso. SJR uses a similar algorithm as the Google fisiopatologiia rank; it provides a quantitative and qualitative measure of the journal’s impact.

Angina de Prinzmetal & Sd de Takotsubo by Diego Cañar on Prezi

Thus, we highlight the importance of determining thyroid hormone concentrations in cases of vasospastic angina, especially when drug resistance is observed, 4 and even if the signs of hyperthyroidism are mild, 2 a circumstance to which previous treatment with beta-blockers can contribute.

Three fisuopatologia after the procedure, he was readmitted with unstable angina after detection of transient precordial ST elevation and slight enzymatic elevation. One year after the initiation of this medication, he was admitted to the hospital with unstable angina, with mild electrical and enzymatic changes.


For the management of this entity, it is essential to control the thyroid activity, which can be curative in itself, obviating the need for subsequent antianginal therapy, 5 especially if there is no accompanying heart disease. We present 2 cases of severe vasospastic angina resistant to intensive medical treatment.

Two weeks later, he was readmitted with the same clinical signs and symptoms and the same electrical changes, prinnzmetal by anxiety and resting tremor. Hospital General Universitario de Alicante. Finally, the patient underwent total thyroidectomy, without subsequent recurrence of anginal fisioptologia, even after the calcium antagonists were discontinued 2 months after the surgical procedure. Images subject to Copyright. Previous Article Vol Are you a health professional able to prescribe or dispense drugs?

The duration of the follow-up period was 14 months. Iberoamerican Cardiovascular Journals Editors’ Network. The journal adheres to the standards of academic research publications in all aspects including peer-review and ethical principles.

These manuscripts contain updated topics with a major clinical or conceptual relevance in modern fusiopatologia. You can change the settings or obtain more information by clicking here. A second catheterization ruled out complications associated with the previously implanted stentas well a development of new lesions, and the patient was discharged on calcium antagonists and nitrates.

Subscribe to our Newsletter. On the other hand, the control of hyperthyroidism proved impossible, despite the use of antithyroid drugs and the discontinuation of amiodarone. SRJ is a prestige metric based on the idea that not all citations are the same.

Forty-eight hours later, a level of free thyroxine of 4. The atenolol that had originally been prescribed was discontinued.

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